Scientific watch


A new study showed the the behavior of children with Autism Spectrum Disorders allows to predict if they have seizures or not

2020, June 22nd


Press Releases


2019, Wednesday 23th January

Fetal brain volume increases during parturition and birth in autism

French Article

2017, Tuesday 14th March

A promising trial to reduce autistic disorders

French Article

2014, Thursday 6th February

Autism: the hormone of delivery would control the syndrome’s expression in the animal

French Article


Scientific Articles



Chiesa M, Nardou R, Lozovaya N, Eftekhari S, Tyzio R, Guimond D, Ferrari DC, Ben-Ari Y.
Enhanced glutamatergic currents at birth in SHANK3 KO mice. Neural Plasticity, 2019.

Lozovaya N, Nardou R, Tyzio R, Chiesa M, Pons-Bennaceur A, Eftekhari S, Bui TT, Billon-Grand M, Rasero J, Bonifazi P, Guimond D, Gaiarsa JL, Ferrari DC, Ben-Ari Y.
Early alterations in a mouse model of Rett syndrome: the GABA developmental shift is abolished at birth. Scientific Reports, 9(1), 9276. Source

Cloarec R, Riffault B, Dufour A, Rabiei H, Gouty-Colomer LA, Dumon C, Guimond D, Bonifazi P, Eftekhari S, Lozovaya N, Ferrari DC, Ben-Ari Y.
Pyramidal neuron growth and increased hippocampal volume during labor and birth in autism. Science Advances, 23 Jan 201; 5-1.


Fernandez A,Dumon C,Guimond D, Tyzio R,Bonifazi P, Lozovaya N,Burnashev N,Ferrari DC, Ben-Ari Y.
The GABA Developmental Shift Is Abolished by Maternal Immune Activation Already at Birth. Cerebral Cortex, 2018; 1-11.
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Lozovaya N, Ben-Ari Y, Hammond C.
Striatal dual cholinergic/GABAergic transmission in Parkinson disease: friends or foes? Cell Stress, 2018; 2(6):147-149.
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Chiesa M, Guimond D, Tyzio R, Pons-Bennaceur A, Lozovaya A, Burnashev N, Ferrari DC, Ben-Ari Y.
Term or preterm cesarean section delivery does not lead to long-term detrimental consequences in mice. Cerebral Cortex, 2018.
Source ›

Lozovaya N, Eftekhari S, Cloarec R, Gouty-Colomer LA, Dufour A, Riffault N, Billon-Grand M, Pons-Bennaceur A, Oumar N, Burnashev N, Ben-Ari Y, Hammond C.
GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease. Nature communications, 2018; 9(1):1422
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Hadjikhani N, Johnels JA, Lassalle A, Zürcher NR, Hippolyte L, Gillberg C, Lemonnier E, Ben-Ari Y.
Bumetanide for autism: more eye contact, less amygdala activation. Scientific Reports, 2018; 8(1):3602.
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Lemonnier E, Villeneuve N, Sonie S, Serret S, Rosier A, Roue M, Brosset P, Viellard M, Bernoux D, Rondeau S, Thummler S, Ravel D, Ben-Ari Y.
Effects of bumetanide on neurobehavioral function in children and adolescents with autism spectrum disorders. Translational psychiatry, 2017;7(3):1056.
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Lemonnier E, Lazartigues A, Ben-Ari Y.
Treating Schizophrenia With the Diuretic Bumetanide: A Case Report. Clin Neuropharmacol., 2016; 39(2):115-7.
Source ›

Ben-Ari Y.
Progress in autism research and postgenomic studies. The Lancet Neurology, 2016; 15(2):136.
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Ben-Ari Y.
GABA depolarizes immature neurons and inhibits network activity in the neonatal neocortex in vivo. Front Cell Neurosci., 2015; 9:478.
Source ›

Ben-Ari Y.
Is birth a critical period in the pathogenesis of autism spectrum disorders? Nat Rev Neurosci., 2015; 16(8):498-505.
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Tyzio R, Nardou R, Ferrari DC, Tsintsadze T, Shahrokhi A, Eftekhari S, Khalilov I, Tsintsadze V, Brouchoud C, Chazal G, Lemonnier E, Lozovaya N, Burnashev N, Ben-Ari Y.
Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring. Science, 2014; 343(6171): 675-679.
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Eftekhari S, Shahrokhi A, Tsintsadze V, Nardou R, Brouchoud C, Conesa M, Burnashev N, Ferrari DC, Ben-Ari Y.
Response to Comment on “Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring”. Science, 2014; 346(6206): 176.
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Ben-Ari Y.
The GABA excitatory/inhibitory developmental sequence: a personal journey. Neuroscience, 2014; 279:187-219.
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Lemonnier E, Robin G, Degrez C, Tyzio R, Grandgeorge M, Ben-Ari Y.
Treating Fragile X syndrome with the diuretic bumetanide: a case report. Acta Paediatr. 2013; 102(6):e288-90.
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Nardou R, Ferrari DC, Ben-Ari Y.
Mechanisms and effects of seizures in the immature brain. Semin Fetal Neonatal Med., 2013; 18(4):175-84.
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E Lemonnier, C Degrez, M Phelep, R Tyzio, F Josse, M Grandgeorge, N Hadjikhani and Y Ben-Ari.
A randomised controlled trial of bumetanide in the treatment of autism in children. Translational Psychiatry, 2012; 2:e202.
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Ben-Ari Y, Khalilov I, Kahle KT, Cherubini E.
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders. Neuroscientist., 2012; 18(5):467-86.
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2014, Friday 7th November

CRÉA13 : 4th prize

23rd Créa13 Awards organized by the CG13 (Conseil Général des Bouches-du-Rhône)

French movie
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2013, Thursday 14th November

Trophées de l’Économie : 1st prize in the category : « Tremplins La Provence »

18th Economy Awards organized by La Provence

French Article
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2014, Friday 5th to Monday 8th September

EMBO Conference on Brain development and disorders, La Ciotat, France

Autism and related disorders: from bench to bed

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